ITS, it's or its can mean:

• its, the possessive form of it — used to show that something belongs to a generic “it”, e.g., “This computer comes with its own mouse and keyboard.”
• it’s, a contraction of it is or it has
• it’s, an archaic possessive of “it” — this usage died out after it’s replaced ‘tis for the generally used contraction of it is “It’s (versus Its), Cats and Catsup, Landscape, Right (versus Left, et al.), and a visit from The Willies”. The Word Detecive.
• "It's" man, a man with torn clothes and unkempt beard who appeared at the beginning of episodes of Monty Python's Flying Circus

Computing

• Incompatible Timesharing System, a computer operating system
• Internet technical support, the people you call to repair your Internet connection
• Intelligent tutoring system, an artificial intelligence system used for tutoring
• Issue tracking system, computer software packages that manage and maintain lists of issues, as needed by an organization
• Information Technology Services, a generic name for a computer support department

Education

• Institute of Technology, Sligo, Ireland
• Institut Teknologi Sepuluh Nopember, in Surabaya, Indonesia
• Intelligent tutoring system, an artificial intelligence system used for tutoring

Science and engineering

• ITS-90, or International Temperature Scale, which provides the defining points for temperature
• Internal transcribed spacer, a section of DNA located within a set of ribosomal genes
• Intelligent transportation system, using technology to improve the efficiency of roads

Notes

ITS | ITS