IDC is an initialism that can stand for:
- IDC scripting language, used in IDA Pro Interactive Disassembler
- indirect costs, in financial contexts, otherwise known as "facilities and administrative costs"
- Interdisciplinary Center, a college in Herzliya, Israel
- Insane Detail Club, a group of people at Scifi-meshes.com known for their ultra-high detail 3D models *
- Insulation-displacement connector, a connector that pierces the insulation on a wire to make the connection
- International Data Corporation, the consulting company, subsidiary of International Data Group
- Internet data center, a place established by a service provider to provide stable and wide-band networks and high performance computers as a service to their customers
- Iris Deactivation Code, in the Stargate SG-1 TV show, a code sent through an open stargate to request the iris be opened
- iDevCenter, a Persian website for Iranian programmers and web developers *
- "I don't care.", Internet slang used in Instant Messenger conversations.
- Infiltrating ductal carcinoma
- "In due course"
- Iris deactivation code is Stargate SG-1