Guadalupe (or Guadeloupe) may refer to:

• The Basilica of Guadalupe, Mexico City
• Guadalupe, a city part of the metropolitan area of Monterrey, Mexico
• Villa de Guadalupe, a former town near Mexico City
• Guadalupe, a village near Tecate, Baja California, Mexico
• Guadalupe, in Puebla, Mexico
• Guadalupe, in Zacatecas, Mexico
• Guadalupe, a town in Spain
• Santa María de Guadalupe, a monastery in this town
• Isla de Guadalupe, a small island of Mexico
• Guadalupe, a town in Arizona
• Guadalupe, a city in California
• Guadeloupe, a French overseas département
• Guadalupe, a town in Brazil
• Guadalupe, a suburb of San Jose, Costa Rica
• Guadalupe, a barangay located in the northeastern part of Cebu City
• Guadalupe, a common name in Spanish-speaking countries, particularly Mexico
• Guadalupe Victoria, nom de guerre of the first President of Mexico
• Guadalupe Parrondo, a Mexican concert pianist
• Guadelupe, A town in Peru
• Guadalupe River, a river in Texas

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