Great Famine can refer to multiple historical famines that refer to themselves as the "Great Famine".

• Great Famine of 1315-1317 - Northern European famine of the 14th century.
• Great Irish Famine (1740-1741) - 18th century, called by some the "Forgotten Famine," due to its obscurity relative to the later famine of 1845-49.
• Irish Potato Famine (1845-1849) - 19th century cause of a great exodus of Irish, forming what is now the Irish diaspora of the Americas, Australia, etc.
• Holodomor - Ukraine 1932-33
• Ethiopian famine