The Grammy Award for Best Pop Instrumental Performance has been awarded since 1969.

• In 1969 it was awarded as Best Contemporary-Pop Performance, Instrumental
• From 1970 to 1971 it was awarded as Best Contemporary Instrumental Performance
• In 1972 it was awarded as Best Pop Instrumental Performance
• In 1973 it was awarded as Best Pop Instrumental Performance by an Instrumental Performer
• From 1974 to 1975 it was again awarded as Best Pop Instrumental Performance
• From 1986 to 1989 it was awarded as Best Pop Instrumental Performance (Orchestra, Group or Soloist)
• Since 1990 it has again been awarded as Best Pop Instrumental Performance

A similar award for Best Instrumental Performance was awarded from 1965 to 1968. This was also in the pop field, but did not specify pop music.

Years reflect the year in which the Grammy Awards were presented, for works released in the previous year.

2000s

• Grammy Awards of 2006
  • Les Paul for "Caravan"
• Grammy Awards of 2005
  • Ben Harper for "11th Commandment"
• Grammy Awards of 2004
  • George Harrison for "Marwa Blues"
• Grammy Awards of 2003
  • B. B. King for "Auld Lang Syne"
• Grammy Awards of 2002
  • Eric Clapton for "Reptile"
• Grammy Awards of 2001
  • Brian Setzer for "Caravan" performed by the Brian Setzer Orchestra
• Grammy Awards of 2000
  • Santana for "El Farol"

1990s

• Grammy Awards of 1999
  • Brian Setzer for "Sleepwalk" performed by The Brian Setzer Orchestra
• Grammy Awards of 1998
  • Sarah McLachlan for "Last Dance"
• Grammy Awards of 1997
  • Béla Fleck and the Flecktones for "The Sinister Minister"
• Grammy Awards of 1996
  • Los Lobos for "Mariachi Suite"
• Grammy Awards of 1995
  • Booker T. & the M.G.'s for "Cruisin' "
• Grammy Awards of 1994
  • Branford Marsalis & Bruce Hornsby for "Barcelona Mona"
• Grammy Awards of 1993
  • Richard Kaufman (conductor) for "Beauty and the Beast"
• Grammy Awards of 1992
  • Michael Kamen for Prince of Thieves
• Grammy Awards of 1991
  • Angelo Badalamenti for "Twin Peaks Theme"
• Grammy Awards of 1990
  • The Neville Brothers for "Healing Chant"

1980s

• Grammy Awards of 1989
  • David Sanborn for Close-up
• Grammy Awards of 1988
  • Larry Carlton for "Minute By Minute"
• Grammy Awards of 1987
  • Harold Faltermeyer & Steve Stevens for "Top Gun Anthem"
• Grammy Awards of 1986
  • Jan Hammer for "Miami Vice Theme"
• Grammy Awards of 1985
  • Ray Parker Jr. for "Ghostbusters (Instrumental)"
• Grammy Awards of 1984
  • George Benson for "Being With You"
• Grammy Awards of 1983
  • Ernie Watts for "Chariots of Fire Theme (Dance Version)"
• Grammy Awards of 1982
  • Larry Carlton & Mike Post for "The Theme From Hill Street Blues"
• Grammy Awards of 1981
  • Bob James & Earl Klugh for One on One
• Grammy Awards of 1980
  • Herb Alpert for "Rise"

1970s

• Grammy Awards of 1979
  • Chuck Mangione for Children of Sanchez
• Grammy Awards of 1978
  • John Williams for A New Hope Soundtrack
• Grammy Awards of 1977
  • George Benson for "Breezin'"
• Grammy Awards of 1976
  • Van McCoy for "The Hustle"
• Grammy Awards of 1975
  • Marvin Hamlisch for "The Entertainer"
• Grammy Awards of 1974
  • Eumir Deodato for "Also Sprach Zarathustra ( A Space Odyssey (film))"
• Grammy Awards of 1973
  • Billy Preston for "Outa-Space"
• Grammy Awards of 1972
  • Quincy Jones for Smackwater Jack
• Grammy Awards of 1971
  • Henry Mancini for Theme From Z and Other Film Music
• Grammy Awards of 1970
  • Blood, Sweat & Tears for "Variations on a Theme by Eric Satie"

1960s

• Grammy Awards of 1969
  • Mason Williams for "Classical Gas"

Grammy Awards for pop music