Gamma glutamyl transferase (GGT or GGTP, or Gamma-GT) () is a liver enzyme. The enzyme is also present in other tissues, such as the epididymis. Its level in the blood may be tested for, as an elevated level may indicate an abnormality in the liver, though this can be caused by a number of conditions including:

• congestive heart failure
• cholestasis (congestion of the bile ducts)
• cirrhosis of the liver
• Restricted blood flow to the liver
• Necrosis of the liver
• Liver tumors
• hepatitis
• hepatotoxic drugs

Its levels are increased in chronic and acute alcohol abuse.

References

Chemical pathology | EC 2.3.2

Gamma glutamil transpeptidasa | Gamma glutamyl transpeptidase | Γ-glutamylotranspeptydaza