Gainsborough may refer to:

• Several places in England:
  • Gainsborough, Lincolnshire
  • An area in Ipswich
  • Gainsborough Area in Kiama Downs

• Aerith Gainsborough, a character from Final Fantasy VII
• Thomas Gainsborough, a painter (who is often referred to simply as Gainsborough)
• Humphrey Gainsborough, Thomas's brother
• Gainsborough Pictures, a London-based film studio, active between 1924 and 1951
• Gainsborough Central School, an elementary school in Bismark, Ontario
• Gainsborough (racehorse), the 1918 Triple Crown Champion of British Thoroughbred Racing

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