Dubin-Johnson syndrome is an autosomal recessive disease which presents shortly after birth with an increase of conjugated bilirubin without elevation of liver enzymes (ALT, AST). There's a mutation in canalicular multispesific organic anion transporter which causes dysfunction on bilirubin transfer to bile canaliculi. Prognosis is good and there's no need to treat this syndrome.

See also

• Jaundice
• Gilbert syndrome
• Crigler-Najjar syndrome
• Rotor syndrome

External links

• Dubin-Johnson syndrome - emedicine.com

Eponymous diseases | Gastroenterology | Hepatology

Dubin-Johnson-Syndrom | Zespół Dubina-Johnsona