The Dniprodzerzhynsk Reservoir () is a water reservoir located on the lower part of the Dnieper River in Ukraine. Named after the city of Dniprodzerzhynsk, it covers a total area of 567 square kilometres within the Dnipropetrovsk Oblast. It was formed in 1963-1965. The reservoir is mainly used for generating hydroelectric power, transportation, fish farming, and human consumption The reservoir is 114 km in length, 5 km in width (8 km max.); has a depth of 15 meters, and a volume of 2.45 km³. During winter, the reservoir freezes over.

The ports of Kremenchuk and the Dnieper Mineral Enrichment Complex in Komsomolsk are located on the reservoir. The Dniprodzerzhynsk Hydroelectric Station, constructed during 1956–1965, is also located on the reservoir.

Reservoirs in Ukraine