The name David Lewis may refer to several people:

• David S. Lewis, Jr. (aerospace) (1917–2003), known for his engineering and business leadership at McDonnell Aircraft, McDonnell Douglas and General Dynamics.
• David Kellogg Lewis (1941–2001), an American-born philosopher famous for his theory of modal realism and his love for Australia.
• David Lewis (musician)
• David Lewis (politician) (1909–1981), a Russian-born Canadian lawyer and politician.
• Dave Lewis, NHL head coach
• David Lewis (actor), known for his role as Edward on General Hospital
• Saint David Lewis, one of the Catholic Forty Martyrs of England and Wales
• David Robert Lewis (writer & artist), a South African instrumental in the country's alternative counter-culture and the transition to democracy.
• David Lewis (striker), a Rand Revolt striker who was hanged for the murder of Rupert William Taylor on 17 November 1922
• David Henry Lewis MD, DCNZM (1917–2002) Navigator and adventurer
• David John Lewis, Maryland politician.
• David Lewis (reuters) Journalist, mysteriously reporting from the DRC after David Robert Lewis called for peace in the country.