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The acronym DBS may stand for the following, depending on context:
- Aston Martin DBS – an automobile model of the Aston Martin brand
- Aston Martin DBS V12 – an automobile model of the Aston Martin brand
- DBS Bank – the largest bank in South East Asia, based in Singapore
- Deep brain stimulation
- Den Beste Sykkel (lit. "The Best Bike") – a Norwegian bicycle brand and manufacturer
- Diocesan Boys' School, a boys-only secondary school in Hong Kong
- Direct broadcast satellite
- Dublin Business School, a private business college in Dublin, Ireland established in 1975
- Danaher Business System, lean manufacturing business model implemented by the Danaher Corporation.
- Dibutyl sebacate
"DBS"