Chlorpheniramine and phenylpropanolamine are often combined to form an allergy medication with both antihistamine and decongestant properties.

Brand names include Demazin®, Allerest 12 Hour®, Chlornade®, Contac 12 Hour®, A. R. M. Allergy Relief®, Ordrine®, Ornade Spansules®, Teldrin®, and Triaminic®.