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Cytochrome P450 2E1 (abbreviated CYP2E1, ), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics in the body. While it is involved only in the oxidative metabolism of a small range of substrates (mostly small polar molecules), there are some important drug interactions mediated by CYP2E1.

CYP2E1 Ligands


  1. Where classes of agents are listed, there may be exceptions within the class.
Selected inducers, inhibitors and substrates of CYP2E11
Type Agent
inducers acetone, ethanol, isoniazid
inhibitors cimetidine, disulfiram, (isoniazid)?
substrates anaesthetics (halothane, isoflurane, etc), dapsone, paracetamol (acetaminophen), theophylline
Notes:

See also


Cytochrome P450 | EC 1.14.14

 

This article is licensed under the GNU Free Documentation License. It uses material from the "CYP2E1".

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