Cytochrome P450 2C8 (abbreviated CYP2C8), a member of the cytochrome P450 mixed-function oxidase system, is involved in the metabolism of xenobiotics in the body.
| Selected inducers, inhibitors and substrates of CYP2C81 | |
| Type | Agent |
| inducers | rifampicin |
| inhibitors | gemfibrozil, glitazones (rosiglitazone, pioglitazone, etc), montelukast, quercetin, trimethoprim |
| substrates | cerivastatin, paclitaxel, repaglinide, torasemide |
| Notes: | |