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Allodynia, meaning "other pain", is an exaggerated response to otherwise non-noxious stimuli and can be either static or mechanical. Allodynia is not referred pain and can occur in other areas that are not stimulated; it is also dysesthetic.

For example, a person with Allodynia may perceive light pressure or the movement of clothes over the skin as painful, whereas a "normal" individual will not feel pain.

One explanation of the mechanism for Allodynia is that the associated nerve damage results in decreased firing thresholds of nociceptive fibres.

Alternatively, it has been postulated that peripheral nerve injury could induce collateral sprouting of non-nociceptive primary afferent neurones, such as A-beta low threshold mechanoreceptors, into the superficial (nociceptive) laminae in the dorsal horn of the spinal cord. These collateral branches could form functional contacts with nociceptive second order neurones, normally innervated by C-fibre nociceptive primary afferent neurones and transmit an innocous input as noxious.

There are different kinds of Allodynia:

  • Mechanical allodynia (also known as tactile allodynia) - Pain from light touch/pressure applied to the skin in the area of the damaged nerve.
  • Thermal allodynia - Pain from normally mild skin temperatures in the affected area.

Pain

Allodynie | Allodynie | Allodynia

 

This article is licensed under the GNU Free Documentation License. It uses material from the "Allodynia".

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