Airline has several meanings:

• Airline is the common term for commercial aviation transportation service using aircraft.
• Formerly, a synonym for beeline, or the shortest path between two land points regardless of obstacle. As defined by a 1913 dictionary: "Air line, a straight line; a bee line. Hence Air-line, adj.; as, air-line road." (As of 2005 this meaning has fallen into disuse).
  • See Air Line Railroad for railroads named in that manner.
  • The Bangor-Calais leg of State Route 9 (Maine) is "The Airline".
  • The Airline Highway in Louisiana.
  • Airline Highway, a portion of former US-16 near Muskegon, Michigan.
• Airline - TV show aired in the UK on ITV1 and in the USA on A&E Network
• Another spelling of "air line", a tube that carries a compressed air supply, e.g. to inflate tyres or power compressed-air tools.
• Airlines (computer game), an MS-DOS based airline management simulation game.
• Airline 5/6, a computer simulation game developed in Australia to simulate owning and operating an airline anywhere in the world.