| 2C-E | |
|---|---|
| Chemical name | 2,5-Dimethoxy-4-ethyl-phenethylamine or 1-(2,5-dimethoxy-4-ethylphenyl)-2-aminoethane |
| Chemical formula | C12H19NO2 |
| Molecular mass | 209.28 g/mol |
| Melting point | - |
| CAS number | 71539-34-9 |
| SMILES | NCCC1=C(OC)C=C(CC)C(OC)=C1 |
2C-E (2,5-dimethoxy-4-ethylphenethylamine) is a psychedelic drug and phenethylamine first synthesized by Alexander Shulgin, sometimes used as an entheogen. It is commonly active in the 10-20 mg range, taken orally, and highly dose-sensitive. Insufflating (ie administering the chemical nasally) requires a much lower dose, typically not exceeding 5mgs, but tends to cause intense pain. Shulgin classified 2C-E as a member of the "magical half-dozen" in his book PiHKAL. Many have reported that the effects of 2C-E are similar to those of the other phenethylamines, only much more intense. Vivid hallucinations similar to those experienced while under the influence of LSD are common, and many reports would indicate that the effects of this particular chemical may be overly intense for those not well experienced with psychedelics. However, for those who are familiar with the compound, oral doses of 30+ mg are not uncommon and often show no additional side effects beyond those already described.
As compared to similar compounds such as 2C-I and 2C-B, 2C-E has much more of an emphasis on synaesthesia, music, and closed-eye visuals.
The body load (ie. nausea and physical strain induced by ingestion) tends to be fairly minor in the typical dose range overall, but it seems to be somewhat inconsistent between individuals.
In Sweden, 2C-E has been controlled since Oct 1, 2004.
The UK has the strictest laws in the EU on designer drugs. The Misuse Of Drugs Act was amended in 2002 to include a "catch most" clause outlawing every drug, and possible future drug, from the LSD (tryptamine) and ecstasy (phenethylamine) chemical families (including 2C-E). The amendment is a virtual cut-and-paste from the books of the respected American biochemist Alexander Shulgin, who obtained a PhD from the University of California, Berkeley. Dr Shulgin, a former research chemist at the Dow Chemical Company, re-discovered the recipe for MDMA in 1976 and published the recipes for more than 170 designer drugs of his own invention.