1-Aminocyclopropane-1-carboxylic acid (ACC) is a disubstituted cyclic amino acid. The three-membered cycle is attached to the C(alpha)-atom.

ACC plays an important role in the biosynthesis of the herbal hormone ethylene. It is synthesized by ACC synthase enzyme from methionine and converted to ethylene by ACC oxidase.

ACC is also a non-physiological partial agonist of the mammalian NMDA receptor.

Notes

1. Inanobe A, Furukawa H, Gouaux E. (2005). "Mechanism of Partial Agonist Action at the NR1 Subunit of NMDA Receptors." Neuron, 47(1):71-84.
2. Source of information for Infobox: MetaCyc Compound Record; retrieved July 15, 2005. Reference: Cynthia J. Krieger, Peifen Zhang, Lukas A. Mueller, Alfred Wang, Suzanne Paley,Martha Arnaud, John Pick, Seung Y. Rhee and Peter D. Karp (2004). MetaCyc: a multiorganism database of metabolic pathways and enzymes. Nucleic Acids Research, 32:D438-D442.

Cyclic amino acids

Aminocyclopropancarbonsäure